Late Show with David Letterman
S22 E51 • Jake Gyllenhaal, Dr. John P. Holdren, Nico & Vinz
Episodes

Luke Wilson, Julie Chen, Lee Brice
No description available.

Kristen Wiig, Sen. Elizabeth Warren, The New Pornographers
No description available.

Steve Buscemi, Indy Car Season Champ, Alt-J
No description available.

Tina Fey, Moody McCarthy, Kevin Drew
No description available.

Bill Maher, Henrik Lundqvist, Spoon
No description available.

Michael Strahan, Richard Branson, Interpol
No description available.

Dr. Phil, Katharine McPhee, Death from Above 1979, Ray Benson
No description available.

Jason Bateman, Billy Eichner, Ryan Adams
No description available.

Mindy Kaling, Jake Johannsen, Maddie & Tae
No description available.

Mark Harmon, "Jungle" Jack Hanna
No description available.

Denzel Washington, Lenny Kravitz
No description available.

Kelly Ripa, Jim Gaffigan, Paloma Faith
No description available.

Jerry Seinfeld, Michael Jackson ONE
No description available.

Ted Danson, Andrew Norelli
No description available.

Neil Patrick Harris, Jamie Oliver, Aretha Franklin
No description available.

John Oliver, Maggie Q, Bleachers
No description available.

Bill O'Reilly, Cristin Milioti
No description available.

Johnny Galecki, Andre Benjamin, Delta Spirit
No description available.

Mariska Hargitay, Simon Amstell, Kandace Springs
No description available.

Aziz Ansari, Tom Dreesen
No description available.

Robert Downey Jr., Sarah Paulson, Lizzo
No description available.

Anderson Cooper, Gina Rodriguez, Hatsune Miku
No description available.

Robert Duvall, Elle Fanning, Rival Sons
No description available.

Chelsea Handler; Keegan-Michael Key and Jordan Peele; Angaleena Presley
TV host Chelsea Handler; comics Keegan-Michael Key and Jordan Peele; Angaleena Presley performs.

Russell Brand, Dave Grohl, Foo Fighters
No description available.

Michael Keaton, Foo Fighters
No description available.

Bill Murray, Foo Fighters
No description available.

Tom Selleck, Jenny Slate, Foo Fighters
No description available.

Jessica Chastain, Lenny Marcus, Foo Fighters
No description available.

Amy Poehler, Sen. Jeff Flake, Sen. Martin Heinrich, Mastodon, Jerry Lee Lewis
No description available.

Taylor Swift, Tom Mison
No description available.

Jim Carrey, David Tennant
No description available.

Brian Williams, Perfume Genius
No description available.

Keith Olbermann, Brian Regan, Run the Jewels
No description available.

Martin Short, Father John Misty
No description available.

Jennifer Lopez, Rob Riggle, Kimbra
No description available.

Whoopi Goldberg, Jimmy Page, Mapei
No description available.

Amy Schumer, Jeff Caldwell
No description available.

Katie Holmes, Alex Zanardi
No description available.

Steve Carell, Martha Stewart, OK Go
No description available.

Jennifer Lawrence, Boris Johnson
No description available.

Jon Stewart, Shawn Mendes
No description available.

Kristin Chenoweth; Chris Young
Actress Kristin Chenoweth; Chris Young performs.

Jason Sudeikis, Allison Janney, Damien Rice
No description available.

Stupid Pet Tricks, Charlie Day, Hiss Golden Messenger
No description available.

Regis Philbin, Hundred Waters
No description available.

Edward Norton, Jessye Norman
No description available.

Norman Lear, TV on the Radio
No description available.

Seth Rogen, Amy Sedaris
No description available.

Emily Blunt, Adam Resnick, Wu-Tang Clan
No description available.

Jake Gyllenhaal, Dr. John P. Holdren, Nico & Vinz
No description available.

Joaquin Phoenix, Cristela Alonzo, Al Green
No description available.

Ben Stiller, Olivia Munn, LaLa Brooks
No description available.

Meryl Streep, Rebel Wilson, J. Cole
No description available.

Chris Rock, Sting
No description available.

Jamie Foxx, Robert Klein, Dan Penn
No description available.

Emma Stone Top, Marcus Mariota, Bob Seger
No description available.

New Holiday Toys, Anna Kendrick, Charli XCX
No description available.

Tom Brokaw, Will Nelson & Billy Joe Shaver
No description available.

Rosie O’Donnel,l Jeff Altman
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Jay Thomas, Josh Brolin, Darlene Love
The final Christmas episode. Jay Thomas drops by to once again tell "The best talk show story, ever", then he and David try to knock the meatball off the Christmas tree in the Late Show Quarterback Challenge. An interview with Josh Brolin. The show wraps up with Darlene Love's last Late Show performance of Christmas (Baby Please Come Home).

Kathy Griffin, David Oyelowo, Lera Lynn
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Ethan Hawke, Allison Williams, Parquet Courts
No description available.

Julianne Moore, Catfish & the Bottlemen
No description available.

Donald Trump, Chelsea Peretti, Foxygen
No description available.

Michael Somerville, Nicole Atkins
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Gordon Ramsay, Adam Devine, St. Paul and the Broken Bones
No description available.

Anderson Cooper, Shovels & Rope
No description available.

Amanda Peet, Ryn Weaver
No description available.

Larry David, Dan Patrick, Sleater-Kinney
No description available.

Urban Meyer, Johnny Beehner, Ella Henderson
No description available.

Louis CK, Nicolle Wallace, the Lone Bellow
No description available.

Andrew Luck, Oscar Isaac, Drenge
No description available.

Viola Davis, Ben Schwartz, Marty Stuart
No description available.

John Oliver, Mayim Bialik, Death Cab for Cutie
No description available.

Aziz Ansari, Brian Kiley, Ben Howard
No description available.

Jack Hanna, Sharon Jones and the Dap-Kings
No description available.

Dr. Phil McGraw, Robin Tunney, Diana Krall
No description available.

Ryan Reynolds, Dierks Bentley
No description available.

Martin Short, Bettye Lavette
No description available.

Sienna Miller, Andy Kindler, Bob Mould
No description available.

Steve Carell, Dr. Cornel West
No description available.

Courtney Love, Chris Elliott, Rhiannon Giddens
No description available.

Bill Belichick, Elisabeth Moss, Madisen Ward and the Mama Bear
No description available.

Tom Hanks, Sturgill Simpson
No description available.

Bill Hader, Pat McGann, Shakey Graves
No description available.

Matthew Perry, Adam Scott, Kishi Bashi
No description available.

Dakota Johnson, David Tochinskiy, Twin Shadow
No description available.

Will Smith, Grizfolk
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Don Cheadle, Ilana Glazer & Abbi Jacobson, Mikky Ekko
No description available.

Kid Scientists, Sean Hayes, Judah & the Lion
No description available.

Helen Mirren, the 2015 Daytona 500 winner, Steve Earle
No description available.

Matthew Broderick, Ellie Kemper, JD McPherson
No description available.

Julianna Margulies, Eric Ripert, Glass Animals
No description available.

Kevin Spacey, Lily James, Alabama Shakes
No description available.

Patricia Arquette, Will Butler
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Kelsey Grammer, Stevie Wonder
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Lena Dunham, Bobby Cannavale, Andy Kim with Kevin Drew
No description available.

Kevin Bacon, Jimmie Walker, Airborne Toxic Event
No description available.

Shailene Woodley, Dr. Cornel West, Matthew E. White
No description available.

Will Ferrell, Glen Hansard
No description available.

Norm MacDonald, Theo James
No description available.

Ben Stiller, Tove Lo
No description available.

Bill O'Reilly, Aubrey Plaza
No description available.

James Franco, Jake Johannsen, Action Bronson
No description available.

Neil Patrick Harris, Charlie Cox, the Suffers
No description available.

David Duchovny, Josh Gad, Houndmouth
No description available.

Sen. Al Franken, Billy Eichner, David Sanborn
No description available.

Kelly Ripa, Aasif Mandvi, Fat White Family
No description available.

Mike Myers, Nick Griffin, Banks
No description available.

Sarah Jessica Parker, Julie Chen, Asleep at the Wheel
No description available.

Billy Crystal, Chris Russo, Chris Stapleton
No description available.

Michael J. Fox, Iron & Wine, Ben Bridwell
No description available.

Kevin James, Tom Dreesen, Tracy Chapman
No description available.

Alec Baldwin, John Mayer
No description available.

John Travolta, Amy Schumer, the Waterboys
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Piedmont Bird Callers, Paul Rudd
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Bruce Willis, Dawes
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Robert Downey Jr., Chris Russo, Elvis Costello
No description available.

Jerry Seinfeld, Jason Isbell & Amanda Shires
No description available.

Scarlett Johansson, John Mellencamp, Todd Rundgren
No description available.

Michael Keaton, Future Islands
No description available.

Jack Hanna, John Popper
No description available.

First Lady Michelle Obama Hootie and the Blowfish
No description available.

Steve Martin, Emmylou Harris, Rodney Crowell, Amos Lee, Ralph Stanley, Mark O'Connor
No description available.

President Barack Obama, Will Ferrell, the Avett Brothers, Brandi Carlile
No description available.

Reese Witherspoon, Nathan Lane, Mumford & Sons
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Martin Short, Norah Jones
No description available.

Tina Fey, First Aid Kit
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Ray Romano, Brian Regan, Dave Matthews Band
No description available.

Howard Stern, Don Rickles
No description available.

Bill Clinton, Adam Sandler
No description available.

Julia Roberts, Paul Shaffer, Ryan Adams
No description available.

Al Pacino, George Clooney, Tom Waits
No description available.

Oprah Winfrey, Norm Macdonald
No description available.

Tom Hanks, Eddie Vedder
6.0No description available.

Bill Murray, Bob Dylan
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The Final Late Show with David Letterman
6.06,028th broadcast

Episode 149
The final episode includes surprises, memorable highlights and the last Top Ten List.